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Imaging of Isotopically Enhanced Molecular Targeting Agents Final Report
The goal of this project is to develop experimental and computational protocols to use SIMS to image the chemical composition of biological samples, focusing on optimizing sample preparation protocols and developing multivariate data analysis methods. Our results on sample preparation, molecular imaging, and multivariate analysis have been presented at several meeting abstracts (UCRL151797ABS, UCRL151797ABSREV1, UCRL151426ABS, UCRL201277, UCRL154757). A refereed paper describing our results fordoi:10.2172/15009794 fatcat:kx36zpzjnzg65hrad553pr7p2u