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Bordbar A, Palsson BO (University of California San Diego, La Jolla, CA, USA). Using the reconstructed genome-scale human metabolic network to study physiology and pathology (Key Symposium). J Intern Med 2012; 271: 131-141. Metabolism plays a key role in many major human diseases. Generation of high-throughput omics data has ushered in a new era of systems biology. Genome-scale metabolic network reconstructions provide a platform to interpret omics data in a biochemically meaningful manner. Thedoi:10.1111/j.1365-2796.2011.02494.x pmid:22142339 pmcid:PMC3243107 fatcat:tpexhn5n5jh3xg6kpku5yz5boe