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Von Willebrand disease is the most common hereditary bleeding disorder; its Type 3 is the most severe form with a high risk for surgical bleeding, both intraoperatively and during the postoperative period. Despite that, there is a scarcity of data describing the management of these patients undergoing surgical procedures. We report on a 55-years-old woman with a long history of Von Willebrand disease type 3, who had an emergency laparoscopic cholecystectomy performed using VWF/FVIII concentratedoi:10.36959/831/381 fatcat:5onizg3qqjhsfnse6vvcb4bqqy