Chromatoid body and haploid gene activity: Actinomycin D induced morphological alterations

LEENA-MAIJA PARVINEN, PENTTI T. JOKELAINEN, MARTTI PARVINEN
2009 Hereditas  
Arbor, Mich., U . S . A . PARVINEN, L.-M., JOKELAINEN, P. T. and PARVINEN, M. 1978. Chromatoid body and haploid gene activity: Actinomycin D induced morphological alterations. -Hereditas 88:75-80. Lund, Sweden. ISSN 0018-0661. Received November 1 1 , 1977 New evidence about the dependence of the chromatoid body on the haploid gene activity during early spermiogenesis has been obtained in rats by morphological studies after intratesticular injection of Actinomycin D. Normally, this organelle
more » ... s an irregularly lobulated structure of dense filamentous material but following AMD administration, it appears as a ring in the electron microscopic sections, in the phase contrast microscopic and light microscopic preparations of living and sectioned material. The alterations appeared 12 h after the injection, which corresponds to the time required for the incorporation of the radioactivity to this organelle after a pulse with tritiated uridine.
doi:10.1111/j.1601-5223.1978.tb01605.x pmid:649426 fatcat:n5mziyyu65awrkbrcioyilr6a4