Single mutidrug resistant enterobacteriacae donor-derived infection in four solid organ transplant recipients: a case report

Eva Kieslichova, Marek Protus, Dana Nemcova, Eva Uchytilova
2019 BMC Surgery  
Bacteraemia of the donor is not considered to be contraindication of organ procurement. On the other hand, infection of solid organ transplant recipients remains to be a major cause of their morbidity and mortality. When using organs from bacteraemic donors, individual risks need to be assessed and the appropriate antibiotic treatment applied. Case presentation: In this case series we report several serious donor-derived infectious complications in four out of five recipients of different
more » ... from one single donor in the early posttransplant period. Donor-transmitted multi-drug resistant strains of Escherichia coli and Klebsiella pneumonia was confirmed by both serologic and molecular testing. Conclusions: To prevent donor-derived infections, careful microbiological screening followed by targeted antibiotic treatment is essential. Although such complications can never by completely prevented, a high index for potential bacterial infection in organ donors and transplant recipients should be routinely employed.
doi:10.1186/s12893-019-0574-9 fatcat:uyfqv6hgznf35nzi67duuwuoja