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Stressful events induce a range of neurochemical and endocrine changes as part of the brain's adaptive response to such challenges. If the organism is repeatedly stressed, the development or exacerbation of psychopathologies, such as depression and anxiety, can ensue. A potential role for inflammatory factors in these disorders has emerged. In the present experiment, we investigated whether a challenge with interleukin (IL)-6, a pro-inflammatory cytokine commonly associated with depression,doi:10.22215/etd/2013-09899 fatcat:f3zvwsk5knht5ggr4qr6fkzsb4