Solvation of Parachloro Meta Xylenol (PCMX) in AlcoholsAqueous Solutions at 293.15 K

2016 International Journal of Advanced Research in Chemical Science  
The densities and the refractive indices of ethanol, methanol and glycerol mixtures with water by ratios of (0.00-0.5104 mole fraction of alcohols) were measured at 293.15 ºK. The densities, molal solubility and refractive indices of PCMX in the ethanol, methanol and glycerol-water mixtures by ratios of (0.00-0.5104 mole fraction of alcohols) were measured at 293.15 ºK. The apparent molal volume (V Q ), the Wander Wall volume (V w ), the electrostriction volume (V e ) and the solvated radius
more » ... of PCMX in the above solvent mixtures were calculated and discussed. Also, the molar refraction, the polarizability and the atomic polarization of PCMX in the ethanol, methanol and glycerol-water mixtures by ratios of (0.00-0.5104 mole fraction of alcohols) were measured at 293.15 ºK were calculated and discussed. The result indicate that, as the concentrations of ethanol and methanol in alcohols-water mixtures increase, the densities of solvent (d º ) and PCMX solutions (d) decrease and the refractive indices in both solvent and solution mixtures increase. It also noted that, increase of concentrations of glycerol-water mixtures resulted in increase in the refractive indices and density of the solvents and solutions. The spectra of PCMX in ethanol-water mixtures by ratios of (0.00-0.5104 mole fraction of alcohols) were measured at 293.15 ºK. The spectra show a hyper chromic effect as the percentage of ethanol increased. EXPERIMENTAL Materials and Solutions Ethanol (C 2 H 5 OH) (95%), Methanol (CH 3 OH) (95%) and Glycerol (C 3 H 8 O 3 ) (99.5%) are from ELNASR Pharmaceutical chemicals Co.(Egypt). PCMX (Scheme 1) was from Royal Co., Egypt.Alcohols-water mixtures of different ratios (0-0.5104mole fraction of alcohols) were prepared using bidistilled water. Saturated solutions of PCMX were prepared in alcohols-water mixtures of different ratios (0.00-0.5104 mole fraction of alcohols) at 293.15 ºK. Farid I. El-Dossoki et al. Apparatus and Procedure Spectrophotometer of a type Jenway was used to measure the spectra of PCMX and Abe refractometer was used to measure the refractive index (±0.0001) of the solvents and the solutions at 293.15 K. Digital balance of four decimal was used to measure the weight. Ultrathermostate of type Kottermann 4130 was used to adjust the temperature degree at the select degree (±0.01 ºK).After, Alcohols-water mixtures of different ratios (0.0-0.5104 mole fraction of alcohols) were prepared, the density and refractive indices were measured. The density was measured by weighting 1 ml of solvent (±0.0001). Saturated solutions of PCMX were prepared in alcohols-water mixtures of different ratios (0.00-0.5104 mole fraction of alcohols) at 293.15 ºK by adding excess PCMX solid compound for 2 weeks till complete saturation and equilibrium stablishing. After that, filtration was done and one ml of clear filtrate was taken and weight (d value) then evaporated till constant weight. RESULTS AND DISCUSSION Solubility Measurements The density of methanol, ethanol and glycerol-water mixtures of a different ratios (0.00-0.5104 mole fraction of alcohols) and of PCMX in methanol, ethanol and glycerol-water mixtures of a different ratios (0.00-0.5104 mole fraction of alcohols) were measured as explained in the experimental section. The density values were tabulated in Tables 1-3 and represented in Figures 1-3. Table1. The density of the solvent mixtures, d˚, and the density, d, the molality, m, the solvated radius, r , the apparent molal volume, V Q the Wander Wall volume, V w the electrostriction volume, V e and the solvation free energy change (∆G s ) of the PCMX, in different methanol mole fractions in water mixtures at 293.15 K and Pressure (p = 0.1 MPa) a Methanol Vol. %
doi:10.20431/2349-0403.0309003 fatcat:kjjl4czp5fhwhcs2sx2wf4tl7q