GFP: A Quantitative Indicator of the Amount of Lipid Rafts in Yeast Cell

Sushanta Sarkar
2017 MOJ Bioequivalence & Bioavailability  
Lipid rafts (LR) are cholesterol-enriched micro domains of the cell membrane and possess a highly dynamic nature. Lipid rafts have been implicated in signaling pathways and in cancer progression. We emit the hypothesis that the amount of lipid rafts vary from healthy to cancerous cells and that certain conditions such as larger production of cholesterol may be the cause of cancer production. The aim is to analyze the binding property of GFP and cholesterol in Saccharomyces cerevisiae (Sc) cell
more » ... embrane. Saccharomyces cerevisiae (Sc) cell is very good candidates for studying the lipid contents of their membrane. Finally, the aim of this review is to validate the possibility of studying lipid rafts to make a connection between lipid content of cell membrane with cause of cancer.
doi:10.15406/mojbb.2017.03.00026 fatcat:ue4va6zht5fb3ofoya4ds7m62u