Regenerative Potential of Immunocompetent Cells

P. Nettesheim, T. Makinodan, M. L. Williams
1967 Journal of Immunology  
The principal findings reported in this communication are: 1) the minimum antigen dose necessary to initiate a near maximum antibody response is about 105 times greater for irradiated than for unirradiated spleen cells, and 2) the compartment of immunologically committed progenitor cells (PC2) lacks the potential to recover from an x-ray insult and appears not to have significant self-generating potential.
doi:10.4049/jimmunol.99.1.150 fatcat:priqm52uqzetlirsacmw6dcibe