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Anticonvulsant activity of ethanolic extract and aqueous fraction of Launaea acanthodes gum in comparison with diazepam in mice
Launaea acanthodes gum (LAG) contains flavonoids with benzodiazepine-like activity and so it may be helpful in treatment of epilepsy. Objective: To determine the effects of ethanolic extract (EE) and aqueous fraction (AF) of LAG on convulsion induced by pentylentetrazole (PTZ) in mice. Methods: This experimental study was carried out at the (Iran) in 2005. Lethal doses (LD50) of EE and AF were determined by acute toxicity test. The effect of AF on activity of brain was investigated by usingfatcat:qr4b3475zvdkjincidc2c6hb6y