Atypical Brain Torque in Boys With Developmental Stuttering

Jeffrey Ryan Mock, Janet N. Zadina, David M. Corey, Jeremy D. Cohen, Lisa C. Lemen, Anne L. Foundas
2012 Developmental Neuropsychology  
The counterclockwise brain torque, defined as a larger right prefrontal and left parietal-occipital lobe, is a consistent brain asymmetry. Reduced or reversed lobar asymmetries are markers of atypical cerebral laterality and have been found in adults who stutter. It was hypothesized that atypical brain torque would be more common in children who stutter. MRI-based morphology measures were completed in boys who stutter (n=14) and controls (n=14), ages 8-13. The controls had the expected brain
more » ... que configurations whereas the boys who stutter were atypical. These results support the hypothesis that developmental stuttering is associated with atypical prefrontal and parietal-occipital lobe asymmetries. Asymmetry Quotients-AQs were analyzed by one-way ANOVA with Group as the single grouping factor using the same hierarchical levels as described above to control for Type I error rate. Structure-Function Relationships-Pearson correlation (r) was used to assess relationships between anatomical measures and average SLD rate in the boys who stutter, and language measures in both groups. RESULTS Cognitive Measures General Cognition-No group differences in IQ (Full scale, Verbal or Spatial) scores were detected (F (1,26) = 0.01, p = 0.93; boys who stutter = 109.8 ± 24.6, controls = 108.6 ± 11.9) Mock et al.
doi:10.1080/87565641.2012.661816 pmid:22799762 pmcid:PMC5537737 fatcat:joljo5awvjhgza3g36k5z6bgo4