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Cystinuria is an aminoaciduria caused by mutations in the genes that encode the two subunits of the amino acid transport system b 0,+ , responsible for the renal reabsorption of cystine and dibasic amino acids. The clinical symptoms of cystinuria relate to nephrolithiasis, due to the precipitation of cystine in urine. Mutations in SLC3A1, which codes for the heavy subunit rBAT, cause cystinuria type A, whereas mutations in SLC7A9, which encodes the light subunit b 0,+ AT, cause cystinuria typedoi:10.1371/journal.pone.0137277 pmid:26359869 pmcid:PMC4567282 fatcat:nbxpgpt4znaazft3xbzzubipby