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A novel dual mode capacitor biosensor for real-time, label-free DNA detection
2006
2006 International Electron Devices Meeting
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An ellipsometry-based biosensor, the oblique-incidence reflectivity difference (OI-RD) scanning microscope, was developed for label-free, real-time, and in-situ detection of biomolecular interactions. We successfully demonstrate that DNA-DNA hybridization and DNA-protein reactions in a DNA microarray can be monitored by such an OI-RD microscope.
doi:10.1109/iedm.2006.346886
fatcat:ykvita4iqfganaphjuk7tcb3wu