A novel dual mode capacitor biosensor for real-time, label-free DNA detection

Y.-B. Wang, Y. Assefaw-Redda, M. Gabig-Ciminska, S.-O. Enfors, M. Ostling, S.-L. Zhang
2006 2006 International Electron Devices Meeting  
An ellipsometry-based biosensor, the oblique-incidence reflectivity difference (OI-RD) scanning microscope, was developed for label-free, real-time, and in-situ detection of biomolecular interactions. We successfully demonstrate that DNA-DNA hybridization and DNA-protein reactions in a DNA microarray can be monitored by such an OI-RD microscope.
doi:10.1109/iedm.2006.346886 fatcat:ykvita4iqfganaphjuk7tcb3wu