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Mathematical modeling of vertebrate limb development
2013
Mathematical Biosciences
In this paper, we review several main mathematical and computational models of vertebrate limb development and their roles in accounting for different aspects of this process. The main aspects of limb development have been modeled, including outgrowth and shaping of the limb bud, establishment of molecular gradients within the bud, and formation of the skeleton. These processes occur interdependently during development, although (as described in this review), there are various interpretations
doi:10.1016/j.mbs.2012.11.003
pmid:23219575
fatcat:p3w3rhokv5fj3i3cmkssw3sdpq