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Different genetic investigation methods used to determine the effect of genetic factors on the development of dental caries and other human multifactory methods diseases have been described. In particular, clinical-genealogical, beparous, dermatoglyphic methods as well as associations of blood group systems АВ0, RH and HLA have been used. The outlooks of application of morphogenetical investigation method for the study of functional state of somatic cells genome have been analyzed. The study ofdoi:10.11603/2311-9624.2016.3.6838 fatcat:smheoeiosrb7jjxnlxntergaia