Перспективи вивчення генетичних і епігенетичних чинників у виникненні та розвитку карієсу зубів

O. V. Litynska, H. M. Melnychuk, L. Ye. Kovalchuk
Different genetic investigation methods used to determine the effect of genetic factors on the development of dental caries and other human multifactory methods diseases have been described. In particular, clinical-genealogical, beparous, dermatoglyphic methods as well as associations of blood group systems АВ0, RH and HLA have been used. The outlooks of application of morphogenetical investigation method for the study of functional state of somatic cells genome have been analyzed. The study of
more » ... lyzed. The study of genetic and epigenetic mechanism of chromatization degree in caries emergence and development will allow to receive new scientific data that will complement and expand the existing expertise in this sphere. It may become the basis for the development of etiologically and pathogenetically proved methods of dental caries treatment and prevention.
doi:10.11603/2311-9624.2016.3.6838 fatcat:smheoeiosrb7jjxnlxntergaia