Dapsone hypersensitivity syndrome - A case report

Selvalaxmi Gnanasegaran, Mangaiarkkarasi Adhimoolam, Srija Gopal
2017 National Journal of Physiology, Pharmacy and Pharmacology  
Dapsone is widely used for the treatment of leprosy and other immunological and inflammatory dermatological conditions such as dermatitis herpetiformis, vesiculobullous dermatoses, and pustular psoriasis. Dapsone hypersensitivity syndrome (DHS) is a rare reaction associated with fever, skin eruptions, and internal organs involvement. We report a case of DHS who presented with fever, productive cough, dyspnea, skin rashes, and jaundice. Leukocytosis, eosinophilia, and altered liver enzymes were
more » ... liver enzymes were observed in laboratory investigations and patient improved with conservative management.
doi:10.5455/njppp.2017.7.1042308112017 fatcat:4iwyq7vupzaxzlc2bf32fltjta