An Attempt to Apply TEST SKIN 2TM on Cytotoxicity Test

Koichi IMAI, Katsutoshi KAYAMA, Makoto TAKEDA, Masaaki NAKAMURA
1995 The Journal of the Japanese Society for Dental Materials and Devices  
To elucidate the effect of dental materials on oral mucous membrane , an attempt was made to examine cytotoxicity of 3 types of denture base resins and 2 types of resin monomers utilizing commercially a available tissue model , TEST SKIN2TM . It was found that heat and micro − wave curing resins d正d not show cytotoxicity , as indicated in previous reports . However , self curing resins and monomers MMA and TEGDMA showed strong cytotoxicity , which contradicted previous reports . It seemed that
more » ... he mode of specimen contact with the cells contributed to the results . It was also noted that further improvement was needed for efficient use in cytot 〔 } xicity testing of dental materials .
doi:10.18939/jjdm.14.5_499 fatcat:fgqlh43wevhm7fxpuyxb3blzli