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Emerging therapies for mitochondrial disorders
2016
Brain
Mitochondrial disorders are a diverse group of debilitating conditions resulting from nuclear and mitochondrial DNA mutations that affect multiple organs, often including the central and peripheral nervous system. Despite major advances in our understanding of the molecular mechanisms, effective treatments have not been forthcoming. For over five decades patients have been treated with different vitamins, co-factors and nutritional supplements, but with no proven benefit. There is therefore a
doi:10.1093/brain/aww081
pmid:27190030
pmcid:PMC4892756
fatcat:h63gnd7xu5b7rot4iffeep5gke