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Antarctic environments as a source of bacterial and fungal therapeutic enzymes
2022
Anais da Academia Brasileira de Ciências
Microbial therapeutic enzymes are the protagonists in the pharmacological treatment of different human diseases. The intrinsic enzymatic characteristics, such as high affinity and specificity to the corresponding substrate, enable effective therapies, with minimal adverse effects and complete remission. However, immunogenicity, short half-life, low enzymatic yield, and low selectivity regarding available enzyme drugs are currently the main obstacles to their development and the broad adherence
doi:10.1590/0001-3765202220210452
pmid:35170668
fatcat:26vng4xg3zajdcqrmeogcn3piu