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Properties of Ryr3 Ryanodine Receptor Isoform in Mammalian Brain
1996
Journal of Biological Chemistry
Although the RNA for the third isoform (Ryr3) of ryanodine receptor (RyR), a Ca 2؉ release channel, is detected in specific regions of mammalian brain, little is known about the protein. We investigated Ryr3 in rabbit brain, using an antibody raised against the synthetic peptide corresponding to amino acid sequence 4375-4387 of rabbit Ryr3, the homologue of bullfrog -RyR. The antibody which reacted with bullfrog -RyR, but not with the other isoforms, Ryr1 or Ryr2, specifically precipitated a
doi:10.1074/jbc.271.9.5079
pmid:8617786
fatcat:hjagaalt7bhtldnfyhs4rvgy2u