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Evaluation of phylogenetic reconstruction methods using bacterial whole genomes: a simulation based study
2018
Wellcome Open Research
Phylogenetic reconstruction is a necessary first step in many Background analyses which use whole genome sequence data from bacterial populations. There are many available methods to infer phylogenies, and these have various advantages and disadvantages, but few unbiased comparisons of the range of approaches have been made. : We simulated data from a defined "true tree" using a realistic Methods evolutionary model. We built phylogenies from this data using a range of methods, and compared
doi:10.12688/wellcomeopenres.14265.2
pmid:29774245
pmcid:PMC5930550
fatcat:zhunmonr6be3nezwueh3r3a4ny