A Pilot Study for Evaluating a Nation-wide School-based Influenza Vaccination Program in Taiwan

J.H. Chuang, P.I. Lee, W.J. Su, M.T. Liu, Y.L. Liu, P.Y. Chen, Y.F. Huang, T.C. Chan
2008 International Journal of Infectious Diseases  
e142 13th International Congress on Infectious Diseases Abstracts, Poster Presentations serum samples was performed according to the WHO standard method. Results: 9 of 13 isolates in type 1, 23 of 25 isolates in type 2 and 16 of 29 isolates in type 3 were virulent VDPVs. Seropositivities against the virulent type 1 and 2 VDPVs were more than 90%, but the values against the virulent type 3 VDPVs were approximately 60%. Also, neutralizing antibody titers against the virulent type 3 VDPVs were the
more » ... pe 3 VDPVs were the lowest in comparison with the titers against the virulent type 1 and 2 VDPVs. Conclusion: Our results suggest that Japan's vaccination policy, a 2-dose administration of OPV, might be enough to prevent an epidemic of poliomyelitis caused by virulent type 1, 2 and 3 VDPVs, even though the seropositivity and antibody titers against type 3 viruses were the lowest. However, a booster dose of the vaccine for the type 3 virus is recommended.
doi:10.1016/j.ijid.2008.05.354 fatcat:p4h7k362lzag7ku7x2rnh4j7ji