A study was carried out in Ndongo stream, located in Buea, from May to October 2017, to assess the water quality and evaluate the structure of benthic macroinvertebrates. Physicochemical analysis showed that water from Ndongo was well oxygenated (82.21 ± 6.59 %), slightly acidic (pH=6.82 ± 0.22 UC) and alkaline with low quantities of nitrogen compound (2.9 ± 3.57 mg/L NO3+; 0.02 ± 0.02 mg/L NO2– and 0.89 ± 1.78 mg/L NH4+). Regarding the biology of macroinvertebrates, a total of 2058 individuals

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... were collected and identified into 4 phyla, 5 classes, 11 orders, 32 families and belonging to 44 genera. The Shannon & Weaver and Pielou evenness reveal that the benthic macroinvertebrates were more diversified in upstream.