IgG4-Related Airway Involvement Which Developed in a Patient Receiving Corticosteroid Therapy for Autoimmune Pancreatitis

Hiroshi Yamamoto, Masanori Yasuo, Yayoi Nomura, Toshihiko Agatsuma, Atsuhito Ushiki, Toshiki Yokoyama, Kazuhisa Urushihata, Masayuki Hanaoka, Tomonobu Koizumi, Mai Iwaya, Akihiko Yoshizawa, Satoshi Kawakami (+3 others)
2011 Internal medicine (Tokyo. 1992)  
A 66-year-old man was diagnosed with autoimmune pancreatitis in February 2009 and started 40 mg of oral prednisolone followed by a maintenance dose of 5 mg daily. The patient developed a cough in October 2010 and visited our division. He had a high serum concentration of immunoglobulin (Ig) G4 and his chest computed tomography showed airway stenosis without bilateral hilar lymphadenopathy (BHL). The bronchial biopsy specimens revealed lymphoplasmacytic infiltrations with
more » ... -positive/IgG-positive plasma cells of more than 50%. Thus, we diagnosed the airway lesion with IgG4-related airway involvement. This is the first report of a patient with IgG4-related airway involvement without BHL.
doi:10.2169/internalmedicine.50.6220 pmid:22185997 fatcat:64lyr2dttzbidl3txdsfb3lz7e