One of the most pressing problems in modern conditions for the state is forecasting scientific and technological development with the definition of promising strategic directions and innovative technologies. Such forecasting or scientific foresight is necessary for the successful political, economic and social development of the state. Foresight technology is a tool in choosing long-term priorities for the country's development, which will help determine strategic research directions and new

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... hnologies that contribute to the greatest socio-economic effect and the integration of education, science, and production. The article describes the approach developed by the authors, which is to recognize the priority of the development of regional science, which makes it possible to use the potential of university and industry science directly at the locations of production structures. In this regard, the authors substantiate the need to form a mechanism for interaction between higher education and business, which is based on the "triple helix" model, modified taking into account the specifics of mono-industrial regions. With the help of the mechanism proposed by the authors, based on the adapted model of the "triple helix", in which the university plays a system-forming role, the problems of single-industry towns can be solved. Itmotivateslocal businesses to create and implement innovative projects using the scientific potential of the regional university.