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Neuromuscular Blocking Agents
Encyclopedic Reference of Molecular Pharmacology
Key Points • Neuromuscular blocking agents are used to improve conditions for tracheal intubation, to provide immobility during surgery, and to facilitate mechanical ventilation. • The main site of action of neuromuscular blocking agents (muscle relaxants) is on the nicotinic cholinergic receptor at the endplate of muscle. They also have effects at presynaptic receptors located on the nerve terminal. • Succinylcholine is a blocking agent that produces depolarization at the endplate and binds todoi:10.1007/3-540-29719-0_1096 fatcat:5e74olvsdrc7vdtli22nkqpsrm