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Effects of arachidonic acid intake on inflammatory reactions in dextran sodium sulphate-induced colitis in rats
British Journal of Nutrition
AbstractThe aim of this study was to investigate the effects of the administration of oral arachidonic acid (AA) in rats with or without dextran sulphate sodium (DSS)-induced inflammatory bowel disease. Male Wistar rats were administered AA at 0, 5, 35 or 240 mg/kg daily by gavage for 8 weeks. Inflammatory bowel disease was induced by replacing drinking water with 3 % DSS solution during the last 7 d of the AA dosing period. These animals passed loose stools, diarrhoea and red-stained faeces.doi:10.1017/s000711451500224x pmid:26234346 fatcat:vz5ensppdjcvfllts7xc3v445i