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D-Fagomine is an iminosugar found in nature that lowers blood glucose peak after meal and reduces fat-induced weight gain and insulin resistance. The immediate precursor of Dfagomine is accessible straightforward via D-fructose-6-phosphate aldolase catalyzed aldol addition of dihydroxyacetone to Cbz-N-3-aminopropanal (Cbz ¼ benzyloxycarbonyl). In this work, the performance and kinetics of the abovementioned reaction catalyzed by FSA A129G variant was studied. The reaction was investigated indoi:10.1080/00986445.2018.1538975 fatcat:pg2le6vu3jeyjahhzoqfcmgjii