HYPERTRIGLYCERIDAEMIC WAIST PHENOTYPE: ASSOCIATION WITH PREDIABETES AND DIABETES AMONG ADULTS OF CENTRAL KERALA
Journal of Evidence Based Medicine and Healthcare
BACKGROUND Hypertriglyceridaemic waist (HTGW) phenotype has been suggested as a useful screening tool for metabolic abnormalities. AIMS AND OBJECTIVES This study evaluated the association of the hypertriglyceridaemic waist (HTGW) phenotype with prediabetes and diabetes (DM) among adults in central Kerala. SUBJECTS AND METHODS A cross sectional study carried out on adult subjects attending the general medicine outpatient department of a tertiary care centre located in central Kerala. Blood
... Kerala. Blood pressure, anthropometric and metabolic parameters were measured. HTGW was defined as elevated triglycerides and elevated waist circumference. RESULTS Participants with HTGW had odds ratio (95% confidence interval [CI]) of 6.21 (1.83-21.06) in total population, 14.78 (1.70-128.35) in men and 3.14 (0.59-16.67) in women for prediabetes compared to those without HTGW phenotype. Subjects with HTGW phenotype had an odds ratio (95% CI) of 11.60 (6.09-22.11) in total population, 10.23 (4.17-25.07) in men and 13.09 (5.15-33.27) in women for diabetes compared to those without HTGW phenotype. Multivariate analysis showed that age and gender were not independent predictors of Prediabetes and diabetes. CONCLUSION HTGW phenotype was strongly associated with DM and this phenotype could be used as a screening tool to identify adults with diabetes.