Pluripotent Core in Bovine Embryos: A Review [post]

Luis Aguila, Claudia Osycka-Salut, Favian Treulen, Ricardo Felmer
2022 unpublished
Early development in mammals is characterized by the ability of each cell to produce a complete organism plus the extraembryonic, or placental, cells, defined as pluripotency. During subsequent development, pluripotency is lost, and cells begin to differentiate to a particular cell fate. This review summarizes the current knowledge of pluripotency features of bovine embryos cultured in vitro, focusing on the core of pluripotency genes (OCT4, NANOG, SOX2, and CDX2), and main chemical strategies
more » ... or controlling pluripotent networks during early development. Finally, we will discuss the applicability of manipulating pluripotency during morula to blastocyst transition in cattle species.
doi:10.20944/preprints202203.0003.v1 fatcat:vetnzwtp4zf25dt74sgx42yf2q