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Journal of Basic and Clinical PATHOPHYSIOLOGY
and Objective: Vascular endothelial growth factor (VEGF) is a cytokine which is overexpressed in many malignant cancers including leukemia. VEGF plays an important role in tumor invasion and metastasis. Determination of the pattern of VEGF expression in human leukemic cell lines could be useful not only in screening of new antileukemic agents but also to study the mechanism of their action. In the present study, the pattern of VEGF production in some human leukemic cell lines has been assessedfatcat:gvtfnwgpgzhrvluprgn462coba