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Endophytic fungi regarded as fascinating group of organisms colonize the living internal tissues of their host usually higher plants. Endophytes do not cause any symptoms of disease in the host cells and produce natural bioactive compounds considered as an elicitor for plant secondary metabolites production. The present review focused on the biodiversity, surface sterilization, histological localization, isolation methods, colonization frequency, natural products that provide immunity to thedoi:10.4172/1948-5948.s8-004 fatcat:lzgpdw6mwneixee7efofj3mu7m