To improve the results of radiotherapy for laryngeal cancers, (1) altered fractionation schedules, such as hyperf ractionation or accelerated hyperf ractionation, and (2) combined chemotherapy, have recently been used. In our institution, a hyperfractionated and accelerated radiotherapy without a split was performed, to improve the local control probability for early glottic carcinomas. The accelerated fractionation program (AF) consisted of 1.72 Gy per fraction, two fractions per day, 5 days a

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... week, for a total of 55 or 58 Gy. The conventional fractionation program (CF) consisted of five daily fractions of 2 Gy per week, for a total of 64 Gy. The 5-year local control probability for T1 tumors was 80% with CF treatment, whereas with AF it was 87%. For T2 tumors it was 63% with CF, whereas it was 75% with AF. According to combined chemotherapy, concomitant chemoradiotherapy is recently used, and increased preservation rates of the larynx have been reported. Good communication and thorough discussion between otolaryngologists and radiation oncologists are important to select the appropriate modality of treatments and improve preservation of the natural voice.