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Differential Expression of CD11c Defines Two Types of Tissue-Resident Macrophages with Different Origins in Steady-State Salivary Glands
[post]
2021
unpublished
Gland macrophages are primed for gland development and functions through interactions within their niche. However, the phenotype, ontogeny, and function of steady-state salivary gland (SG) macrophages remain unclear. We herein identified CD11c+ and CD11c− subsets among CD64+ macrophages in steady-state murine SGs. CD11c− macrophages were predominant in the SGs of embryonic and newborn mice and decreased with advancing age. CD11c+ macrophages were rarely detected in the embryonic period, but
doi:10.21203/rs.3.rs-590196/v1
fatcat:4qpfobjnhfbx7dakhkas2llec4