Effects of Nicotine Deprivation and Replacement on BOLD-fMRI Response to Smoking Cues as a Function of DRD4 VNTR Genotype

Xiaomeng Xu, Uraina S. Clark, Sean P. David, Richard C. Mulligan, Valerie S. Knopik, John McGeary, James MacKillop, Jeanne McCaffery, Raymond S. Niaura, Lawrence H. Sweet
2014 Nicotine & Tobacco Research  
introduction: Reactivity to smoking cues is an important factor in the motivation to smoke and has been associated with the dopamine receptor 4 variable number tandem repeat (DRD4 exon III VNTR) polymorphism. However, little is known about the associated neural mechanisms.
doi:10.1093/ntr/ntu010 pmid:24659022 pmcid:PMC4072897 fatcat:h3vhyugmqvd2dm5r2ke53hgrje