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Humoral Response Profiling Reveals Pathways to Prostate Cancer Progression
2007
Molecular & Cellular Proteomics
There is considerable evidence for an association between prostate cancer development and inflammation, which results in autoantibody generation against tumor proteins. This immune system-driven amplification of the autoantibody response to intracellular antigens can serve as a sensitive tool to detect low abundance serum proteomic tumor markers for prostate cancer as well as provide insight into biological processes perturbed during cancer development. Here we examine serum humoral responses
doi:10.1074/mcp.m700263-mcp200
pmid:18077443
fatcat:esxprk6qkzeendsnqescvodh6u