Dual visible-light photoredox and palladium(ii) catalysis for dehydrogenative C2-acylation of indoles at room temperature

Manash Kumar Manna, Gurupada Bairy, Ranjan Jana
2017 Organic and biomolecular chemistry  
A mild protocol for direct C2-acylation of indoles with aldehydes is reported at room temperature through the merger of visible light photoredox and palladium(ii) catalysis. Late-stage acylation of tryptophan and selective mono-acylation of carbazoles are also demonstrated.
doi:10.1039/c7ob01418j pmid:28682380 fatcat:yns36mwpw5azjd5mj6ygxzvssa