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A mild protocol for direct C2-acylation of indoles with aldehydes is reported at room temperature through the merger of visible light photoredox and palladium(ii) catalysis. Late-stage acylation of tryptophan and selective mono-acylation of carbazoles are also demonstrated.doi:10.1039/c7ob01418j pmid:28682380 fatcat:yns36mwpw5azjd5mj6ygxzvssa