Metal Free Amino-Oxidation of Electron Rich Alkenes Mediated by an Oxoammonium Salt [post]

Alexandra Millimaci, Rowan Meador, Sara Dampf, John D. Chisholm
2020 unpublished
<div> <div> <div> <p>4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium tetrafluoroborate (Bobbitt's salt) effectively activates electron rich alkenes and promotes the addition of anilines. This transformation provides a direct, transition metal free method for amino-oxidation of alkenes under mild conditions. The relative stereochemistry of the amino-oxidation is influenced by solvent effects, with both the syn and anti amino-oxidation products being accessible from identical starting
more » ... starting materials. </p> </div> </div> </div>
doi:10.26434/chemrxiv.12988682.v1 fatcat:2hcbe25qrrbwjjjthfir5u4w2m