A Concise Synthesis of Barbigerone and Structural Analogues

Youzhe Yang, Chao Wang, Jian Sun
2013 Youji huaxue  
A concise and highly efficient protocol for the synthesis of barbigerone and its structural analogues is reported. Resorcinol was converted to the final products via Friedel-Crafts reaction, pyranoid ring formation, aldol reaction, and oxidation-rearrangement-cyclization with 24%~30% overall yields.
doi:10.6023/cjoc201209011 fatcat:rqrdnrgntngjfdiblelb5f46zu