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SUPERSELECTIVE INTRAARTERIAL INFUSION CHEMOTHERAPY USING HIGH-DOSE CISPLATIN FOR ADVANCED PARANASAL SINUS CARCINOMAS
Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)
Thirty-one patients with advanced paranasal sinus carcinomas received by "two-route" intra-arterial chemotherapy using cis-diamminedichloroplatinum (CDDP) and sodium thiosulfate (STS) to preserve the hard palate and the eye. In these patients, 100 or 150mg/m2 of CDDP was administered weekly through each feeding artery of the tumor superselectively at a rate of 5 mg/min. During the CDDP infusion, a dosage of STS that was two-hundred fold times larger than the CDDP dasage was injected through adoi:10.7248/jjrhi1982.39.4_365 fatcat:rh4ivcozmjaurfd4qms63x7yfe