Single-trial FRPs: A Machine Learning Approach Towards the Study of the Neural Underpinning of Reading Disorders

Christoforos Christoforou, Timothy C. Papadopoulos, Maria Theodorou
2021 Proceedings of the ... International Florida Artificial Intelligence Research Society Conference  
Understanding the neural underpinning of reading disorders, such as dyslexia, is a fundamental question in developmental neuroscience. However, identifying and isolating informative neural components elicited during free-naming paradigms (i.e. unprompted and unconstrained naming tasks) has proven a challenging methodological task. These methodological barriers have hindered the study of the neural underpinnings of reading disorders. In this paper, we proposed a machine learning approach for
more » ... cting neural components during free-naming, overcoming much of the current methodological challenges. We propose a new neural-based metric to differentiate groups of children with dyslexia (DYS) and their chronological age controls (CAC) in a free-naming task. Our approach combines electroencephalography (EEG) and eye-tracking measures to generate single-trial fixation-related potentials (sFRPs) and formulate an optimization problem to extract naming-related neural components, informative of group differences. Our approach is validated on a real dataset involving children with dyslexia and CAC performing a Rapid-Automatized Naming (RAN) task. Our results demonstrate the validity of the proposed metric as an indicator of the neural-based markers of reading disorders. Importantly, our proposed framework provides a novel approach that can facilitate the study of neural correlates of reading disorders under paradigms current methods are unable to.
doi:10.32473/flairs.v34i1.128446 fatcat:iqqnq3ilyvh6pi4v6ea6iekgb4