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Creutzfeldt-Jakob disease
1985
BMJ (Clinical Research Edition)
The prevalence and characteristics of sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease (sCJD) are poorly understood. Methods: Seven consecutive patients with definite sCJD underwent a systematic assessment of sleep-wake disturbances, including clinical history, video-polysomnography, and actigraphy. Extent and distribution of neurodegeneration was estimated by brain autopsy in six patients. Western blot analyses enabling classification and quantification of the protease-resistant
doi:10.1136/bmj.291.6493.483-a
fatcat:tenamnujuzcnfmyiv6shbdmqmu