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The emergence of SARS-CoV-2 variants of concern is driven by acceleration of the evolutionary rate
[article]
2021
medRxiv
pre-print
The ongoing SARS-CoV-2 pandemic has seen an unprecedented amount of rapidly generated genome data. These data have revealed the emergence of lineages with mutations associated to transmissibility and antigenicity, known as variants of concern (VOCs). A striking aspect of VOCs is that many of them involve an unusually large number of defining mutations. Current phylogenetic estimates of the evolutionary rate of SARS-CoV-2 suggest that its genome accrues around 2 mutations per month. However,
doi:10.1101/2021.08.29.21262799
fatcat:eh6mqstzrjhmbo5rduazvwvao4