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Journal of Cancer Immunology & Therapy
Soft tissue sarcomas represent a rare but histologically variable type of solid malignancy. Doxorubicin based regimens either alone or in combination with other agents had remained unchanged for decades as the standard first line treatment for metastatic disease. The definition of metastatic disease has been changed with the introduction of the American Joint Commission on Cancer (AJCC) 8th edition guidelines. The overall survival for patients with metastatic disease, despite the approval of 2doi:10.35841/cancer-immunology.1.1.17-23 fatcat:lr22phrqqzbwpfv6znge3x2lxe