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Effects of trastuzumab on the proliferation and apoptosis of ovarian cancer cells
This study investigates the effects of trastuzumab on the proliferation and apoptosis of ovarian cancer cells. Epithelial ovarian cancer tissues were collected from 60 patients, benign ovarian tissues from 45 patients and normal ovarian tissues from 30 patients. Human epidermal growth factor receptor 2 (HER2) protein expression was measured by immunohistochemistry and mRNA expression by quantitative real-time polymerase chain reaction (RT-PCR). Proliferation and apoptosis of SKOV3 cells weredoi:10.4149/neo_2018_180724n524 fatcat:5hn55hs7ivedzb2rejvmrm2zem