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Quantification of the pace of biological aging in humans through a blood test: the DunedinPACE DNA methylation algorithm
[article]
2021
medRxiv
pre-print
Measures to quantify changes in the pace of biological aging in response to intervention are needed to evaluate geroprotective interventions for humans. Here, we report an advance on our original method (Belsky et al. 2020). We used data from the Dunedin Study 1972-3 birth cohort tracking within-individual decline in 19 organ-system integrity indicators across four timepoints spanning two decades to model Pace of Aging. We distilled two-decade Pace of Aging into a single-time-point
doi:10.1101/2021.08.30.21262858
fatcat:qqu5kwkzd5abpkiib3jrwy3cf4