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Comparison of multi echo T2 relaxation and steady state approaches for myelin imaging in the central nervous system
2021
Scientific Reports
AbstractThe traditional approach for measuring myelin-associated water with quantitative magnetic resonance imaging (MRI) uses multi-echo T2 relaxation data to calculate the myelin water fraction (MWF). A fundamentally different approach, abbreviated "mcDESPOT", uses a more efficient steady-state acquisition to generate an equivalent metric (fM). Although previous studies have demonstrated inherent instability and bias in the complex mcDESPOT analysis procedure, fM has often been used as a
doi:10.1038/s41598-020-80585-7
pmid:33446710
fatcat:bbjdu5kefbcf5olobxdtf5ak3a