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Synthesis and serological interactions of H. pylori urease fragment 321-339 n-terminally immobilized on the cellulose
Acta Poloniae Pharmaceutica - Drug Research
Preserved Fulltext
Antigenic epitopes F8 (SIKEDVQF) and UB-33 (UreB fragment with residues 321-339: CHHLDKSIKEDVQFADSRI) in H. pylori urease that induces neutralizing antibody production were prepared on the cellulose plate from N- to C-terminus using CDMT as a coupling reagent. Reaction of both epitopes with sera of patients with medically confirmed atherosclerosis was studied. Strong, selective reactions of both peptides with some patients sera were observed.
pmid:17203862
fatcat:uiu33kymrjbvhd4qm45fl3lzy4