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Meiotic interactors of a mitotic gene TAO3 revealed by functional analysis of its rare variant
[article]
2015
bioRxiv
pre-print
Studying the molecular consequences of rare genetic variants has the potential of identifying novel and hereto uncharacterized pathways causally contributing to phenotypic variation. Here we characterize the functional consequences of a rare coding variant of TAO3, previously reported to significantly contribute to sporulation efficiency variation in Saccharomyces cerevisiae. During mitosis TAO3 interacts with CBK1, a conserved NDR kinase and a component of RAM network. The RAM network genes
doi:10.1101/033167
fatcat:25rxuthfxzb5dmeh3v2vn7o74y