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We showed the results of the first long-term analysis (1987-2019) of pesticide impact in the main agricultural area of Argentina. Using a clear and meaningful tool, based not only on acute toxicity but also on scaling up the results to total sown area, we identified time trends for both total pesticide impact and the ecoefficiency of modal pesticide profiles. By the end of the time series, soybean showed a pesticide impact four times greater than maize crop in the studied area. However, thedoi:10.1101/2020.09.02.280560 fatcat:fil5rn7zvvbxfjgys2cy7mzymy